|
ThdH
|
A1E280
|
Flavin-dependent
|
Streptomyces albogriseolus
|
None
|
not tested
|
utilized
|
utilized
|
not tested
|
DOI: 10.1002/cbic.202500246
DOI: 10.3390/catal9121030
DOI: 10.1074/jbc.RA118.005393
|
|
MalA
|
L0E155
|
Flavin-dependent
|
Malbranchea aurantiaca
|
in vitro
|
not tested
|
utilized
|
utilized
|
not tested
|
DOI: 10.1021/jacs.7b06773
|
|
VhaA
|
CCD33142.1
|
Flavin-dependent
|
Amycolatopsis orientalis strain ATCC19795
|
in vitro,
in vivo
|
not tested
|
utilized
|
not tested
|
not tested
|
DOI: 10.1039/C4OB00474D
DOI: 10.1039/D0CC07421G
|
|
AetF
|
A0A861B9Z9
|
Flavin-dependent
|
Aetokthonos hydrillicola
|
in vitro
|
not tested
|
not tested
|
utilized
|
utilized
|
DOI: 10.1021/jacs.1c12778
DOI: 10.1107/S2059798323004254
DOI: 10.1002/ange.202214610
DOI: 10.1073/pnas.2409479122
DOI: 10.1002/ange.202317860
|
|
bmp2
|
AKJ75108.1
|
Flavin-dependent
|
Pseudoalteromonas sp. PS5
|
in vitro,
in vivo
|
not tested
|
not utilized
|
utilized
|
not tested?
|
DOI: 10.1073/pnas.1519695113
DOI: 10.1038/nchembio.1564
|
|
LlpH
|
CAM34371.1
|
Flavin-dependent
|
Streptomyces tendae
|
predicted
|
not tested
|
utilized
|
not tested
|
not tested
|
DOI: 10.1016/j.gene.2010.03.016
|
|
HrmQ
|
C1IHU5
|
Flavin-dependent
|
Streptomyces griseoflavus W-384
|
in vivo
|
not tested
|
utilized
|
not tested
|
not tested
|
DOI: 10.1002/cbic.200800186
|
|
flA
|
2C2W
|
SAM-dependent
|
Streptomyces cattleya
|
in vitro
|
utilized
|
utilized
|
not utilized
|
not utilized
|
DOI: 10.1038/nature02280
DOI: 10.1016/s0014-5793(03)00688-4
DOI: 10.1002/anie.200503582
DOI: 10.1039/b600574h
|
|
Nat1
|
ADM46362.1
|
Flavin-dependent
|
Streptomyces sp. CS
|
in vivo
|
not tested
|
utilized
|
not tested
|
not tested
|
DOI: 10.1039/C1MB05036B
|
|
XanJ
|
AAG38844.2
|
Flavin-dependent
|
Xanthomonas oryzae pv. oryzae
|
in vivo
|
not tested
|
not tested
|
utilized
|
not tested
|
DOI: 10.13926/j.cnki.apps.000639
|
|
KtzR
|
A8CF74
|
Flavin-dependent
|
Kutzneria sp. 744
|
in vitro
|
not tested
|
utilized
|
not tested
|
not tested
|
DOI: 10.1021/ja806467a
|
|
AerJ
|
ACM68683.1
|
Flavin-dependent
|
Microcystis aeruginosa
|
predicted
|
not tested
|
utilized
|
not tested
|
not tested
|
DOI: 10.1093/molbev/msn150
|
|
RebH
|
Q8KHZ8
|
Flavin-dependent
|
Lentzea aerocolonigenes
|
in vitro
|
not tested
|
utilized
|
utilized
(if Cl is not present)
|
not utilized
|
DOI: 10.1002/prot.21627
DOI: 10.1002/cbic.202100210
DOI: 10.1002/cbic.201300780
DOI: 10.1021/bi0621213
DOI: 10.1021/ja2089348
DOI: 10.1002/cbic.202100210
|
|
RhoVCPO
|
None
|
Vanadium-dependent
|
Rhodopirellula baltica
|
in vitro
|
not tested
|
utilized
|
utilized
(preferred)
|
not tested
|
|
|
XanH
|
ADE22292.1
|
Flavin-dependent
|
Streptomyces flavogriseus
|
in vitro
|
not tested
|
utilized
|
not tested
|
not tested
|
DOI: 10.1128/AEM.01225-20
DOI: 10.1016/j.chembiol.2012.01.016
|
|
AmVBPO2
|
WP_012165216
|
Vanadium-dependent
|
Acaryochloris marina
|
in vitro
|
not tested
|
utilized
(lower rate compared to bromide)
|
utilized
|
not tested
|
DOI: 10.1002/cbic.201600417
DOI: 10.5281/zenodo.14544279
|
|
BrtJ
|
AOH72611.1
|
Dimetal-carboxylate
|
Synechocystis salina LEGE 06155
|
predicted
|
not tested
|
utilized
|
not tested
|
not tested
|
DOI: 10.1021/acs.jnatprod.6b00351
DOI: 10.1186/s12864-021-07939-x
|
|
flA4
|
CDP39161.1
|
SAM-dependent
|
Streptomyces xinghaiensis
|
in vivo
|
utilized
|
not tested
|
not tested
|
not tested
|
DOI: 10.1039/C6RA00100A
|
|
AnVBPO1
|
P81701
|
Vanadium-dependent
|
Ascophyllum nodosum
|
in vitro
|
not tested
|
not tested
|
utilized
|
not tested
|
DOI: 10.1021/ja004176c
|
|
AnVBPO2
|
HE598751
|
Vanadium-dependent
|
Ascophyllum nodosum
|
in vitro
|
not tested
|
utilized
|
utilized
|
not tested
|
DOI: 10.1016/j.bioorg.2012.05.003
|
|
BarB1
|
Q8GAQ9
|
Non-heme iron alphaketoglutarate-dependent
|
Lyngbya majuscula
|
in vitro
|
not tested
|
utilized
|
not tested
|
not tested
|
DOI: 10.1021/ja060151n
|
|
BarB2
|
Q8GAQ8
|
Non-heme iron alphaketoglutarate-dependent
|
Lyngbya majuscula
|
in vitro
|
not tested
|
utilized
|
not tested
|
not tested
|
DOI: 10.1021/ja060151n
|
|
AoiQ
|
supplementary material
(10.1021/jacs.1c02868)
|
Flavin-dependent
|
Aspergillus oryzae
|
in vitro,
in vivo
|
not tested
|
utilized
|
utilized
|
not tested
|
DOI: 10.1002/anie.201604516
DOI:
10.1021/jacs.1c02868
|
|
BesD
|
WP_014151497
|
Non-heme iron alphaketoglutarate-dependent
|
Streptomyces cattleya
|
in vivo,
in vitro
|
not tested
|
utilized
|
not tested
|
not tested
|
DOI: 10.1038/s41586-019-1020-y
DOI:
10.1038/s41589-019-0355-x
|
|
NapH2
|
ABS50488.1
|
Flavin-dependent
|
Streptomyces sp. CNQ525
|
predicted
|
not tested
|
not tested
|
not tested
|
not tested
|
DOI: 10.1074/jbc.M611046200
|
|
Asm12
|
AAM54090.1
|
Flavin-dependent
|
Actinosynnema pretiosum subsp. auranticum
|
in vivo
|
not tested
|
utilized
|
not tested
|
not tested
|
DOI:
10.1073/pnas.092697199
DOI:
10.1021/ja038166y
|
|
PyrH
|
K7QVV7
|
Flavin-dependent
|
Streptomyces rugosporus
|
in vitro
|
not tested
|
utilized
|
utilized
|
not tested
|
DOI:
10.1101/2022.07.19.500721
DOI:
10.1016/j.jbc.2024.107210
|
|
SatH
|
UPI000996F5C4 (UniParc)
|
Flavin-dependent
|
Streptomyces albus
|
in vitro
|
not tested
|
utilized
|
utilized
|
not tested
|
DOI: 10.1002/biot.202300557
DOI:
10.1002/cbic.201900723
|
|
Tar14
|
W5VG40
|
Flavin-dependent
|
Saccharomonospora piscinae
|
in vivo,
in vitro
|
not tested?
|
utilized
|
utilized
|
not utilized
|
DOI:
10.1002/anie.201901571
|
|
McnD
|
AAZ03553
|
Flavin-dependent
|
Microcystis sp. NIVA-CYA 172/5
|
predicted
|
not tested
|
utilized
|
not tested
|
not tested
|
DOI:
10.1093/molbev/msn150
|
|
MibH
|
5UAO
|
Flavin-dependent
|
Microbispora corallina NRRL 30420
|
in vitro
|
not tested
|
utilized
|
not tested
|
not tested
|
DOI:
10.1021/acschembio.6b01031
|
|
PltA
|
Q4KCZ0
|
Flavin-dependent
|
Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5)
|
in vitro
|
not tested
|
utilized
|
utilized
|
not tested
|
DOI: 10.1073/pnas.0506964102
DOI:
10.1016/j.jsb.2015.09.013
|
|
flA1
|
W0W999
|
SAM-dependent
|
Streptomyces sp. MA37
|
in vivo,
in vitro
|
utilized
|
not tested
|
not tested
|
not tested
|
DOI: 10.1002/cbic.201300732
|
|
Pyr29
|
A3R4S0
|
Flavin-dependent
|
Actinosporangium vitaminophilum
|
predicted
|
not tested
|
utilized
|
not tested
|
not tested
|
DOI: 10.1128/aac.01214-06
|
|
Ram20
|
None
|
Flavin-dependent
|
Actinoplanes sp. ATCC33076
|
in vivo
|
not tested
|
utilized
|
not tested
|
not tested
|
DOI: 10.1007/s00253-015-7014-2
|
|
flA2
|
YP_006809254
|
SAM-dependent
|
Nocardia brasiliensis HUJEG-1 (ATCC 700358)
|
in vivo,
in vitro
|
utilized
|
not tested
|
not tested
|
not tested
|
DOI: 10.1002/cbic.201300732
|
|
PrnC
|
P95482
|
Flavin-dependent
|
Pseudomonas fluorescens BL915
|
in vivo
|
not tested
|
utilized
|
not tested
|
not tested
|
DOI: 10.1128/jb.180.7.1939-1943.1998
DOI:
10.1002/1521-3773(20000703)39:13<2300::AID-ANIE2300>3.0.CO;2-I
DOI:
10.3389/fctls.2023.1231765
|
|
SyrB2
|
Q9RBY6
|
Non-heme iron alphaketoglutarate-dependent
|
Pseudomonas syringae pv. syringae
|
in vitro
|
not tested
|
utilized
|
utilized
|
not tested
|
DOI: 10.1038/nature04544
DOI:
10.1021/bi900109z
DOI:
10.1073/pnas.0504412102
|
|
SpH2
|
A0A1Q4EBW3
|
Flavin-dependent
|
None
|
in vitro
|
not tested
|
utilized
|
utilized
|
not tested
|
DOI: 10.3390/catal11040485
|
|
VaNTH
|
WP_204007738.1
|
Non-heme iron alphaketoglutarate-dependent
|
Virgisporangium aurantiacum
|
in vitro
|
not tested
|
utilized
|
not tested
|
not tested
|
DOI: 10.1038/s41467-024-49147-7
|
|
flA3
|
YP_007949809
|
SAM-dependent
|
Actinoplanes sp. N902-109
|
in vivo,
in vitro
|
utilized
|
not tested
|
not tested
|
not tested
|
DOI: 10.1002/cbic.201300732
|
|
PrnA
|
P95480
|
Flavin-dependent
|
Pseudomonas fluorescens
|
in vitro
|
not tested
|
utilized
|
utilized
|
utilized
(not with natural substrates)
|
DOI: 10.1002/anie.201007896
DOI: 10.1038/s41557-019-0349-z
DOI: 10.1039/c5sc00913h
|
|
Mcl40
|
AGH68925.1
|
Vanadium-dependent
|
Streptomyces sp. strain CNH-189
|
in vivo
|
not tested
|
utilized
|
not utilized
(200 mg/L KCl and 200 mg/L Kbr)
|
not tested
|
DOI: 10.1021/ja305665f
|
|
SgcC3
|
WP_029181876.1
|
Flavin-dependent
|
Streptomyces globisporum
|
in vitro
|
not utilized
(unclear experiment)
|
utilized
|
utilized
|
not utilized
(unclear)
|
DOI: 10.1021/ja072311g
|
|
JamD
|
AAS98776.1
|
Flavin-dependent
|
Lyngbya majuscula
|
in vitro
|
not tested
|
not utilized
|
utilized
(preferred over iodide)
|
utilized
|
DOI: 10.1016/j.chembiol.2004.03.030
DOI: 10.1021/jacs.3c05750
|
|
SpmH
|
A0A1W7D4T7
|
Flavin-dependent
|
Streptomyces marincola
|
in vivo
|
not tested
|
utilized
|
not tested
|
not tested
|
DOI: 10.1039/C8OB02775G
|
|
Mpy16
|
J7H1A1
|
Flavin-dependent
|
Streptomyces sp. CNQ-418
|
in vivo,
in vitro
|
not tested
|
utilized
|
not tested
|
not tested
|
DOI: 10.1021/ja305670f
DOI: 10.1073/pnas.1519695113
|
|
PkHalD
|
WP_046063366.1
|
Non-heme iron alphaketoglutarate-dependent
|
Pseudomonadaceae
|
in vitro
|
not tested
|
utilized
|
not tested?
|
not tested
|
DOI: 10.1038/s41589-019-0355-x
|
|
LdVBPO1
|
AJ491786
|
Vanadium-dependent
|
Laminaria digitata
|
in vivo
|
not tested
|
not utilized
|
utilized
|
utilized
|
DOI: 10.1074/jbc.M300247200
|
|
SalL
|
2Q6I
|
SAM-dependent
|
Salinospora tropica
|
in vivo
|
not utilized
|
utilized
|
utilized
|
utilized
|
DOI: 10.1038/nchembio.2007.56
DOI: 10.1021/acs.jafc.3c08185
|
|
SttH
|
E9P162
|
Flavin-dependent
|
Streptomyces toxytricini (Actinomyces toxytricini)
|
in vitro
|
not tested
|
utilized
|
utilized
|
not tested
|
DOI: 10.1039/C6OB01861K
|
|
LdVBPO2
|
AJ491787
|
Vanadium-dependent
|
Laminaria digitata
|
in vitro
|
not tested
|
not utilized
|
utilized
|
utilized
|
DOI: 10.1074/jbc.M300247200
|
|
NocO
|
QOV09192.1
|
Dimetal-carboxylate
|
Nostoc sp. CCAP 1453/38
|
in vitro
|
not tested
|
utilized
|
not tested
|
not tested
|
DOI: 10.1186/s12864-021-07939-x
DOI: 10.1021/acs.biochem.4c00720
|
|
Mic
|
WP_002752271.1
|
Dimetal-carboxylate
|
Microcystis aeruginosa
|
predicted
|
utilized
|
utilized
|
not tested
|
not tested
|
DOI: 10.1186/s12864-021-07939-x
DOI: 10.1021/acssynbio.2c00389
|
|
SwHalB
|
SDN46247.1
|
Non-heme iron alphaketoglutarate-dependent
|
Streptomyces wuyuanensis
|
in situ,
in vitro
|
not tested
|
utilized
|
utilized
|
not tested
|
DOI: 10.1038/s41589-019-0355-x
|
|
KtzD
|
A8CF92
|
Non-heme iron alphaketoglutarate-dependent
|
Kutzneria sp. (strain 744)
|
in vitro
|
not tested
|
utilized
|
not tested
|
not tested
|
DOI: 10.1021/ja8064667
DOI: 10.1073/pnas.0708242104
|
|
JamE
|
Q6E7K5
|
Non-heme iron alphaketoglutarate-dependent
|
Lyngbya majuscula
|
predicted
|
not tested
|
utilized
|
not tested
|
not tested
|
DOI: 10.1002/cbic.201300345
|
|
SyVHPO2
|
ABI46359.1
|
Vanadium-dependent
|
Synechococcus sp. WH8020
|
in vitro
|
not tested
|
utilized
|
utilized
|
utilized
|
DOI: 10.1111/j.1529-8817.2011.01007.x
|
|
SimX1
|
AAK06806.1
|
Flavin-dependent
|
Streptomyces antibioticus
|
predicted
|
not tested
|
utilized
|
not tested
|
not tested
|
DOI: 10.1128/aac.46.5.1174-1182.2002
|
|
PltM
|
Q4KCZ3
|
Flavin-dependent
|
Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5)
|
in vitro
|
not utilized
|
utilized
|
utilized
|
utilized
|
DOI: 10.1038/s41467-019-09215-9
|
|
SyVHPO2
|
WP_011620573.1
|
Vanadium-dependent
|
Synechococcus sp. CC9311
|
in vitro
|
not tested
|
utilized
|
utilized
|
utilized
|
DOI: 10.1111/j.1529-8817.2011.01007.x
|
|
dAMP2
|
WP_030883106.1
|
Non-heme iron alphaketoglutarate-dependent
|
Streptomyces varsoviensis
|
in vivo
|
not tested
|
utilized
|
not tested
|
not tested
|
DOI: 10.1021/acscatal.2c04608
|
|
dAMP3
|
WP_182876399.1
|
Non-heme iron alphaketoglutarate-dependent
|
Microbispora sp. H10670
|
in vivo
|
not tested
|
utilized
|
not tested
|
not tested
|
DOI: 10.1021/acscatal.2c04608
|
|
NapH4
|
CAJ34369.1
|
Vanadium-dependent
|
Streptomyces sp. CNQ-25
|
predicted
|
not tested
|
utilized
|
not tested
|
not tested
|
DOI: 10.1074/jbc.M611046200
|
|
NocN
|
AKL71647.1
|
Dimetal-carboxylate
|
Nostoc sp. CCAP 1453/38
|
predicted
|
not tested
|
utilized
|
not tested
|
not tested
|
DOI: 10.1186/s12864-021-07939-x
|
|
KthP
|
W7T5C7
|
Non-heme iron alphaketoglutarate-dependent
|
Kutzneria sp. (strain 744)
|
in vitro
|
not tested
|
utilized
|
not tested
|
not tested
|
DOI: 10.1021/bi200656k
|
|
dAMP1
|
WP_158075676.1
|
Non-heme iron alphaketoglutarate-dependent
|
Actinokineospora bangkokensis
|
in vivo
|
not tested
|
utilized
|
not tested
|
not tested
|
DOI: 10.1021/acscatal.2c04608
|
|
Zg-VIPO1
|
zobellia_1262
|
Vanadium-dependent
|
Zobellia galactanivorans
|
in vitro
|
not tested
|
not utilized
|
not utilized
|
utilized
|
DOI: 10.1128/AEM.02430-14
|
|
SaDAH
|
QJD15032.1
|
Non-heme iron alphaketoglutarate-dependent
|
Sinomenium acutum
|
in vitro
|
not tested
|
utilized
|
not tested
|
not tested
|
DOI: 10.1038/s41467-020-15777-w
|
|
MarH1
|
AKH84811.1
|
Vanadium-dependent
|
Streptomyces sp. CNQ-509
|
in vitro
|
not tested
|
utilized
|
utilized
|
not tested
|
DOI: 10.1002/anie.201804351
|
|
VirX1
|
M4SKV1
|
Flavin-dependent
|
Cyanophage Syn10
|
in vitro
|
not tested
|
utilized
|
utilized
|
utilized
(preference)
|
DOI: 10.1038/s41557-019-0349-z
|
|
MarH3
|
WP_047020372.1
|
Vanadium-dependent
|
Streptomyces sp. CNQ-509
|
in vitro
|
not tested
|
utilized
|
utilized
|
not tested
|
DOI: 10.1002/anie.201804351
|
|
AmbO5
|
AKP23998.1
|
Non-heme iron alphaketoglutarate-dependent
|
Fischerella ambigua (strain UTEX 1903)
|
in vitro
|
not tested
|
utilized
|
not tested
|
not tested
|
DOI: 10.1016/bs.mie.2018.02.015
|
|
CmaB
|
A0A8T0C957
|
Non-heme iron alphaketoglutarate-dependent
|
Pseudoalteromonas rubra
|
in vitro
|
not tested
|
utilized
|
not tested
|
not tested
|
DOI: 10.1038/nature03797
|
|
WelO5
|
AHI58816
|
Non-heme iron alphaketoglutarate-dependent
|
Hapalosiphon welwitschii UTEX B 1830
|
in vitro
|
note tested
|
utilized
|
utilized
|
note tested
|
DOI: 10.1016/bs.mie.2018.02.015
DOI: 10.1038/nchembio.2112
|
|
AdaV
|
AKQ99303.1
|
Non-heme iron alphaketoglutarate-dependent
|
Actinomadura sp. ATCC 39365
|
in vivo,
in vitro
|
not tested
|
utilized
|
not tested
|
not tested
|
DOI: 10.1002/anie.201914994
DOI: 10.1021/acscatal.2c04608
|
|
TiaM
|
None
|
Flavin-dependent
|
None
|
in vivo,
in vitro
|
not tested
|
utilized
|
utilized
|
not tested
|
DOI: 10.1021/acs.jnatprod.7b00990, 10.1002/hlca.202000130
DOI: 10.1021/ja109445q
|
|
PhmJ
|
A0A125SL25
|
Flavin-dependent
|
Leptolyngbya sp. ISBN3-Nov-94-8
|
in vitro
|
not tested
|
not tested
|
utilized
|
utilized
|
DOI: 10.1021/jacs.3c05750
DOI: 10.1002/cbic.201500467
|
|
CalO3
|
Q8KND5
|
Flavin-dependent
|
Micromonospora echinospora
|
predicted
|
not tested
|
not tested
|
not tested
|
utilized
|
DOI: 10.1126/science.1072105
|
|
Tcp21
|
CAE53362.1
|
Flavin-dependent
|
Actinoplanes teichomyceticus
|
in vitro
|
not tested
|
utilized
|
not tested
|
not tested
|
DOI: 10.1039/C7SC00460E
|
|
PloK
|
None
|
Flavin-dependent
|
None
|
in vivo
|
not tested
|
utilized
|
not tested
|
not tested
|
DOI: 10.1002/cbic.201900404
|
|
AetA
|
A0A861B8S3
|
Flavin-dependent
|
Aetokthonos hydrillicola
|
in vitro
|
not tested
|
utilized
|
not tested
|
not tested
|
DOI: 10.1021/jacs.1c12778
|
|
ChlB4
|
Q0R4P7
|
Flavin-dependent
|
Streptomyces antibioticus
|
predicted
|
not tested
|
utilized
|
not tested
|
not tested
|
DOI: 10.1016/j.chembiol.2006.03.008
|
|
ColE
|
AKQ09582.1
|
Dimetal-carboxylate
|
Moorena bouillonii PNG
|
predicted
|
not tested
|
utilized
|
not tested
|
not tested
|
DOI: 10.1186/s12864-021-07939-x
DOI: 10.1021/acs.jnatprod.5b00301
|
|
Dbv10
|
Q7WZ81
|
Flavin-dependent
|
Nonomuraea sp. ATCC 39727
|
predicted
|
not tested
|
utilized
|
not tested
|
not tested
|
DOI: 10.1099/mic.0.26507-0
|
|
CtcP
|
AEI98659.1
|
Flavin-dependent
|
Streptomyces aureofaciens
|
in vivo
|
not tested
|
utilized
|
utilized
(barely)
|
not tested
|
DOI: 10.1016/j.ymben.2013.06.003
|
|
CtNTH
|
WP_217394979.1
|
Non-heme iron alphaketoglutarate-dependent
|
Catellatospora tritici
|
in vitro
|
not tested
|
utilized
|
utilized
|
not utilized
|
DOI: 10.1038/s41467-024-49147-7
|
|
ComH
|
AAK81830
|
Flavin-dependent
|
Streptomyces lavendulae
|
predicted
|
not tested
|
utilized
|
not tested
|
not tested
|
DOI: 10.1073/pnas.151246498
|
|
CylC
|
AFV96137.1
|
Dimetal-carboxylate
|
Cylindrospermum licheniforme UTEX B 2014
|
in vivo,
in vitro
|
not tested
|
utilized
|
not tested
|
not tested
|
DOI: 10.1186/s12864-021-07939-x, 10.1038/nchembio.2421
DOI: 10.1021/acs.biochem.4c00720
|
|
End30
|
None
|
Flavin-dependent
|
Actinoplanes sp. ATCC33076
|
in vitro
|
not tested
|
utilized
|
not tested
|
not tested
|
DOI: 10.1007/s00253-015-7014-2
|
|
CoVBPO
|
AF218810
|
Vanadium-dependent
|
Corallina officinalis
|
in vitro
|
not tested
|
not tested
|
utilized
|
utilized
|
DOI: 10.1006/jmbi.2000.3806
DOI: 10.1016/S0162-0134(02)00400-2
|
|
HctB
|
AAY42394.1
|
Non-heme iron alphaketoglutarate-dependent
|
Lyngbya majuscula
|
in vitro
|
not tested
|
utilized
|
utilized
|
not tested
|
DOI: 10.1021/ja503179m, 10.1002/cbic.201300345
DOI: 10.3389/fchem.2018.00513
|
|
Bmp5
|
AHA34038.1
|
Flavin-dependent
|
Pseudoalteromonas phenolica O-BC30
|
in vivo
|
not tested
|
not utilized
|
utilized
|
utilized
|
DOI: 10.1038/nchembio.1564
|
|
BrvH
|
6FRL
|
Flavin-dependent
|
Brevundimonas sp. BAL3
|
in vitro
|
not tested
|
utilized
|
utilized
|
not tested
|
DOI: 10.1371/journal.pone.0196797; 10.1002/cbic.202000444
|
|
CrpH
|
ABM21576.1
|
Flavin-dependent
|
Nostoc sp. ATCC 53789
|
predicted
|
not tested
|
utilized
|
utilized
|
utilized
|
DOI: 10.1021/cb6004307
|
|
KtzQ
|
A8CF75
|
Flavin-dependent
|
Kutzneria sp. (strain 744)
|
in vitro
|
not tested
|
utilized
|
not tested
|
not tested
|
DOI: 10.1073/pnas.0708242104
DOI: 10.1021/ja806467a
|
|
FlA(PtaU1)
|
OPY51785.1
|
SAM-dependent
|
Methanosaeta sp. PtaU1.Bin055
|
in vitro
|
utilized
|
not utilized
|
not tested
|
not tested
|
DOI: 10.1021/acscatal.2c01184
|
|
KrmI
|
UZC79437.1
|
Flavin-dependent
|
Uncultured bacterium clone fosmid pADU2a (Theonella swinhoei WA)
|
in vitro
|
not tested
|
utilized
|
utilized
|
not utilized
|
DOI: 10.1021/acschembio.6b01115
|
|
BhaA
|
CAA76550.1
|
Flavin-dependent
|
Amycolatopsis balhimycina strain DSM 5908
|
in vivo
|
not tested
|
utilized
|
not tested
|
not tested
|
DOI: 10.1128/aac.43.7.1565
DOI: 10.1016/S1074-5521(02)00101-1
|
|
ColD
|
AKQ09581.1
|
Dimetal-carboxylate
|
Moorena bouillonii PNG
|
predicted
|
not tested
|
utilized
|
not tested
|
not tested
|
DOI: 10.1186/s12864-021-07939-x
DOI: 10.1021/acs.jnatprod.5b00301
|
|
CurA
|
3NNJ_1
|
Non-heme iron alphaketoglutarate-dependent
|
Lyngbya majuscula
|
in vitro
|
not tested
|
utilized
|
not tested
|
not tested
|
DOI: 10.1073/pnas.1006738107
|
|
CytC3
|
3GJA
|
Non-heme iron alphaketoglutarate-dependent
|
Streptomyces sp.
|
in vitro
|
not tested
|
utilized
|
utilized
|
not tested
|
DOI: 10.1021/ja8097355, 10.1038/nchembio856, 10.1016/j.chembiol.2006.09.012
DOI: 10.1021/ja076454e
|
|
BorH
|
M9QSI0
|
Flavin-dependent
|
uncultured bacterium (environmental sample)
|
in vitro
|
not tested
|
utilized
|
utilized
|
not tested
|
DOI: 10.1002/cbic.201900667
|
|
CiVCPO
|
P49053
|
Vanadium-dependent
|
Curvularia inaequalis
|
in vitro
|
not tested
|
utilized
|
utilized
|
not tested
|
DOI: 10.1021/acscatal.3c00761, 10.1074/jbc.274.34.23820
DOI: 10.1074/jbc.275.16.11650
|
|
DnHal
|
None
|
Flavin-dependent
|
None
|
in vitro
|
not tested
|
utilized
|
not tested
|
not tested
|
DOI: 10.1007/s12010-022-04304-w
|
|
FasV
|
8ZOP
|
Flavin-dependent
|
Streptomyces sp. N12 W1565
|
in vitro
|
not tested
|
utilized
|
not tested
|
not tested
|
DOI: 10.1002/anie.202418843
|
|
HalB
|
Q71ME2
|
Flavin-dependent
|
Actinoplanes sp. ATCC 33002
|
in vitro
|
not tested
|
utilized
|
not tested
|
not tested
|
DOI: 10.1111/j.1574-6968.2004.tb09718.x
|
|
CmdE
|
Q0VZ69
|
Flavin-dependent
|
Chondromyces crocatus Cm c5
|
in vivo
|
not tested
|
utilized
|
not tested
|
not tested
|
DOI: 10.1016/j.chembiol.2006.06.002
|
|
NapH1
|
ABS50486.1
|
Vanadium-dependent
|
Streptomyces sp. CNQ-25
|
in vitro
|
not tested
|
utilized
(only with addition of bromide, if Cl is the only halide source, then it's inactive)
|
utilized
|
not tested
|
DOI: 10.1021/ja201088k, 10.1074/jbc.M611046200
DOI: 10.1021/acs.biochem.2c00338
|
|
ChlA
|
Q54FI4
|
Flavin-dependent
|
Dictyostelium discoideum (Social amoeba)
|
in vivo,
in vitro
|
not tested
|
utilized
|
not tested
|
not tested
|
DOI: 10.1073/pnas.1001681107
|
|
CndH
|
B9ZUJ5
|
Flavin-dependent
|
Chondromyces crocatus
|
in vivo,
in vitro
|
not tested
|
utilized
|
not tested
|
not tested
|
DOI: 10.1016/j.chembiol.2008.11.005
DOI: 10.1016/j.jmb.2008.10.057
|
|
AmVBPO1
|
WP_012161787
|
Vanadium-dependent
|
Acaryochloris marina
|
predicted
|
not tested
|
not tested
|
not tested
|
not tested
|
DOI: 10.1002/cbic.201600417
|
|
Zg-VIPO2
|
zobellia_2088
|
Vanadium-dependent
|
Zobellia galactanivorans
|
in vitro
|
not tested
|
not utilized
|
not utilized
|
utilized
|
DOI: 10.1128/AEM.02430-14
|
|
CVBPO
|
O81959
|
Vanadium-dependent
|
Corallina pilulifera
|
in vitro
|
not utilized
|
utilized
(by the mutants)
|
utilized
(preferred over Cl)
|
utilized
|
DOI: 10.1110/ps.03496004
DOI: 10.1016/S0021-9258(19)89233-5
|
|
Mcl24
|
AGH68909.1
|
Vanadium-dependent
|
Streptomyces sp. strain CNH-189
|
predicted
|
not tested
|
utilized
|
not utilized
(200 mg/L KCl and 200 mg/L KBr)
|
not tested
|
DOI: 10.1021/ja305665f
|
|
LdVIPO
|
Q4LDE6
|
Vanadium-dependent
|
Laminaria digitata
|
in vitro
|
not tested
|
not utilized
|
utilized
(pH=6.7 and not usilized on pH=5.5)
|
utilized
|
DOI: 10.1021/ct100041x
DOI: 10.1007/s00775-005-0626-8
|
|
CmlS
|
Q9AL91
|
Flavin-dependent
|
Streptomyces venezuelae
|
in vivo
|
not tested
|
utilized
|
not tested
|
not tested
|
DOI: 10.1107/S1744309108043091, 10.1016/j.jmb.2010.01.020
DOI: 10.1099/mic.0.26319-0
|
|
CloHal
|
Q8GHB4
|
Flavin-dependent
|
Streptomyces roseochromogenes subsp. oscitans
|
in vivo
|
not tested
|
utilized
|
not tested
|
not tested
|
DOI: 10.1016/S1074-5521(03)00051-6
|
|
Clz5
|
U6A3L4
|
Flavin-dependent
|
Streptomyces sp. CNH287
|
in vivo
|
not tested
|
utilized
|
not tested
|
not tested
|
DOI: 10.1021/ja409520v
|
|
CtoA
|
A0A0M4KXQ6
|
Flavin-dependent
|
Sorangium cellulosum
|
in vivo
|
not tested
|
utilized
|
utilized
|
not tested
|
DOI: 10.1021/acschembio.5b00523
|
|
Cts4
|
Q53659
|
Flavin-dependent
|
Streptomyces aureofaciens
|
in vivo
|
not tested
|
utilized
|
not tested
|
not tested
|
DOI: 10.1271/bbb.59.1099
|
|
AviH
|
ELS56116
|
Flavin-dependent
|
Streptomyces viridochromogenes Tue57
|
in vivo
|
not tested
|
utilized
|
not tested
|
not tested
|
DOI: 10.1016/S1074-5521(01)00040-0
|
|
LvcH
|
JGI Gene ID: 2802568834
|
Vanadium-dependent
|
Streptomyces sp. CNZ-289
|
in vitro
|
not tested
|
utilized
|
utilized
|
utilized
|
DOI: 10.1021/acs.orglett.4c01869
|