CytC3

Enzyme Information
reference: 10.1021/ja8097355
host: E. coli
test: Crystallography
producer: Streptomyces sp.
phmm-model: NHFe_variant_B.hmm

Gene Data
phmm effect mutation gene_name reference
65 hydrogen bonds with sulfate ion K62 CytC3 DOI: 10.1021/ja8097355
134 None Q131 CytC3 DOI: 10.1021/ja8097355
71 None Y68 CytC3 DOI: 10.1021/ja8097355
107 None E104 CytC3 DOI: 10.1021/ja8097355
121 None H118 CytC3 DOI: 10.1021/ja8097355
240 None H240 CytC3 DOI: 10.1021/ja8097355
236 chloride binding site S236 CytC3 DOI: 10.1021/ja8097355
126 chloride binding site F123 CytC3 DOI: 10.1021/ja8097355
253 active site R253 CytC3 DOI: 10.1021/ja8097355
259 active site R259 CytC3 DOI: 10.1021/ja8097355
123 chloride binding site A120 CytC3 DOI: 10.1021/ja8097355
150 active site; interacts with O1 of alphaketoglutarate W150 CytC3 DOI: 10.1021/ja8097355
148 active site T148 CytC3 DOI: 10.1021/ja8097355
109 active site F106 CytC3 DOI: 10.1021/ja8097355
111 active site; interacts with O4 of alphaketoglutarate K108 CytC3 DOI: 10.1021/ja8097355
128 backbone can interact with alpha-ketoglutarate H125 CytC3 DOI: 10.1021/ja8097355
126 backbone can interact with alpha-ketoglutarate F123 CytC3 DOI: 10.1021/ja8097355
119 side chain can interact with alpha-ketoglutarate; hydrogen bonds with sulfate ion D116 CytC3 DOI: 10.1021/ja8097355
- chloride binding loop LDAISGG CytC3 DOI: 10.1021/ja8097355
- chloride binding loop EYG CytC3 DOI: 10.1021/ja8097355
105 side chain can interact with alpha-ketoglutarate R102 CytC3 DOI: 10.1021/ja8097355