CoVBPO

Enzyme Information

reference: 10.1016/S0162-0134(02)00400-2
host: E. coli
test: MCD assay
producer: Corallina officinalis
phmm-model: VHPO_VBPO.hmm
halide-source: 0.5-50 mM potassium bromide, 0.25-100 mM potassium iodide

Gene Data

phmm	effect	mutation	gene_name	reference
68	(says Glu124 in the paper, it's eather G124 or E126 in the seqeunce) regiospecific modification of 1,3-di-tert-butylindole	Glu124	CoVBPO	DOI: 10.1021/ja004176c
218	regiospecific modification of 1,3-di-tert-butylindole	Asp292	CoVBPO	DOI: 10.1021/ja004176c
-	no chloroperoxidase activity; bromination and iodination	H480A	CoVBPO	DOI: 10.1016/S0162-0134(02)00400-2
-	some residues associated with anion binding site of vanadate cofactor in VBPOs (AF218810; 1QHB; BAA31261; BAA31262; 1QI9A-B; AAC35279)	GSPxHPSYxSGHA	CoVBPO	DOI: 10.1016/S0162-0134(02)00400-2
-	some residues associated with anion binding site of vanadate cofactor in VBPOs (AF218810; 1QHB; BAA31261; BAA31262; 1QI9A-B; AAC35279)	LTxxGEI/LNKLAxNxAxGRxMxGxHYxxDxxxxLLLGE	CoVBPO	DOI: 10.1016/S0162-0134(02)00400-2
321	(says Arg395 in the paper, it's either A395 or R397 in the sequence) regiospecific modification of 1,3-di-tert-butylindole	Arg395	CoVBPO	DOI: 10.1021/ja004176c