BorH

Enzyme Information
reference: 10.1002/cbic.201900667
host: Escherichia coli
note: supplemented with NADH
phmm-model: FDH_all_conventional.hmm
halide-source: NaCl
flavin-reductase: BorF

Gene Data
phmm effect mutation gene_name reference
60 lines the Trp binding pocket V82 BorH DOI: 10.1002/cbic.201900667
- lines the Trp binding pocket; bounds Trp binding pocket H109 BorH DOI: 10.1002/cbic.201900667
- H-bond network; bounds Trp binding pocket P110 BorH DOI: 10.1002/cbic.201900667
- lines the Trp binding pocket; bounds Trp binding pocket F111 BorH DOI: 10.1002/cbic.201900667
- H-bond network G112 BorH DOI: 10.1002/cbic.201900667
398 lines the Trp binding pocket; H-bonf with the Trp carboxylate via the hydroxy group Y454 BorH DOI: 10.1002/cbic.201900667
395 lines the Trp binding pocket Y453 BorH DOI: 10.1002/cbic.201900667
404 Trp alpha-amino group forms a salt bridge with the side chain carboxylate E460 BorH DOI: 10.1002/cbic.201900667
408 H-bond network F464 BorH DOI: 10.1002/cbic.201900667
32 bounds Trp binding pocket V52 BorH DOI: 10.1002/cbic.201900667
33 bounds Trp binding pocket P53 BorH DOI: 10.1002/cbic.201900667
57 putative catalytic residue K79 BorH DOI: 10.1002/cbic.201900667
- lines the Trp binding pocket W465 BorH DOI: 10.1002/cbic.201900667
296 lines the Trp binding pocket S358 BorH DOI: 10.1002/cbic.201900667
295 putative catalytic residue; bounds Trp binding pocket E357 BorH DOI: 10.1002/cbic.201900667
- no detected chlorinated product K79A BorH DOI: 10.1002/cbic.201900667